A Facile Total Synthesis of Hainanensine via an Unusual Rearrangement−Annulation Cascade

2010-04-16T00:00:00Z (GMT) by Zhi-Wei Zhang Wei-Dong Z. Li
A facile total synthesis of hainanensine (<b>1</b>), a structurally unique <i>Cephalotaxus</i> alkaloid, via an effective acid-mediated rearrangement/Friedel−Crafts annulation cascade (<b>7a</b>/<b>7b</b> → <b>8a</b>/<b>8b</b>), is described.