jo400850m_si_002.pdf (3.33 MB)
A Chiral Ruthenium-Monophosphine Catalyst for Asymmetric Addition of Arylboronic Acids to Aryl Aldehydes
journal contribution
posted on 2013-06-21, 00:00 authored by Ke Li, Naifu Hu, Renshi Luo, Weicheng Yuan, Wenjun TangA novel ruthenium catalyst on the
basis of a chiral monophosphorus
ligand is efficient for the asymmetric addition of arylboronic acids
to aryl aldehydes, providing a series of chiral diarylmethanols in
excellent yields and enantioselectivities (up to 92% ee). Preliminary
study has shown that this process is catalyzed by a Ru complex with
a single monophosphorus ligand.