Synthesis of Naphthols by Rh(III)-Catalyzed Domino C–H Activation, Annulation, and Lactonization Using Sulfoxonium Ylide as a Traceless Directing Group Vinayak Hanchate Anil Kumar Kandikere Ramaiah Prabhu 10.1021/acs.orglett.9b03182.s001 https://acs.figshare.com/articles/journal_contribution/Synthesis_of_Naphthols_by_Rh_III_-Catalyzed_Domino_C_H_Activation_Annulation_and_Lactonization_Using_Sulfoxonium_Ylide_as_a_Traceless_Directing_Group/9959735 Sulfoxonium ylide directed C–H activation catalyzed by the Rh­(III)-catalyst has been disclosed. In this study, sulfoxonium ylide functions as a traceless directing group, which reacts with an unsymmetrical alkyne, 4-hydroxy-2-alkynoate, to form the corresponding furanone-fused 1-naphthols. The application of the methodology has been illustrated by synthesizing bromo lactones, which are used as an intermediate in synthesizing photochromic dichroic materials. We have also demonstrated the synthesis of an analogue of fimbricalyx lactone A. 2019-10-09 14:34:54 Annulation sulfoxonium ylide functions synthesizing photochromic dichroic materials analogue Rh Sulfoxonium Ylide application Activation 4- hydroxy -2-alkynoate methodology activation Synthesi Lactonization Naphthol unsymmetrical alkyne furanone-fused 1- naphthols fimbricalyx lactone traceles Traceless Directing Group Sulfoxonium ylide Domino synthesizing bromo lactones synthesis