10.1021/acs.nanolett.9b02565.s001
Pengfei Zhan
Pengfei
Zhan
Steffen Both
Steffen
Both
Thomas Weiss
Thomas
Weiss
Na Liu
Na
Liu
DNA-Assembled Multilayer Sliding Nanosystems
American Chemical Society
2019
DNA-Assembled Multilayer Sliding Nanosystems DNA nanotechnology
DNA fuels
origami filaments
gold nanoparticles
gold nanoparticles cross-link DNA origami filaments
DNA-assembled
DNA origami
work seeds
nanoarchitecture
nanoscale elements
2019-08-28 14:04:38
Journal contribution
https://acs.figshare.com/articles/journal_contribution/DNA-Assembled_Multilayer_Sliding_Nanosystems/9742265
DNA nanotechnology
allows for the realization of complex nanoarchitectures
in which the spatial arrangements of different constituents and most
functions can be enabled by DNA. When optically active components
are integrated in such systems, the resulting nanoarchitectures not
only provide great insights into the self-assembly of nanoscale elements
in a systematic way but also impart tailored optical functionality
to DNA origami. In this Letter, we demonstrate DNA-assembled multilayer
nanosystems, which can carry out coordinated and reversible sliding
motion powered by DNA fuels. Gold nanoparticles cross-link DNA origami
filaments to define the configurations of the multilayer nanoarchitectures
as well as to mediate relative sliding between the neighboring origami
filaments. Meanwhile, the gold nanoparticles serve as optical probes
to dynamically interact with the fluorophores tethered on the filaments,
rendering in situ detection of the stepwise sliding processes possible.
This work seeds the basis to implement DNA-assembled complex optical
nanoarchitectures with programmability and addressability, advancing
the field with new momentum.