%0 Journal Article
%A Miao, Maozhong
%A Jin, Mengchao
%A Chen, Panpan
%A Wang, Lei
%A Zhang, Shouzhi
%A Ren, Hongjun
%D 2019
%T Iron(III)-Mediated Bicyclization of 1,2-Allenyl Aryl
Ketones: Assembly of Indanone-Fused Polycyclic Scaffolds and Dibenzo[a,e]pentalene Derivatives
%U https://acs.figshare.com/articles/journal_contribution/Iron_III_-Mediated_Bicyclization_of_1_2-Allenyl_Aryl_Ketones_Assembly_of_Indanone-Fused_Polycyclic_Scaffolds_and_Dibenzo_i_a_i_i_e_i_pentalene_Derivatives/8862356
%R 10.1021/acs.orglett.9b02079.s001
%2 https://acs.figshare.com/ndownloader/files/16243826
%K indanone-fused
%K unsymmetrical
%K umpolung
%K Allenyl
%K dibenzo
%K Herein
%K furnishing
%K Indanone-Fused Polycyclic Scaffolds
%K functionalized polycyclic arrays
%K Assembly
%K Bicyclization
%K Nazarov
%K allenyl
%K indanone-containing blocks
%K 4π-
%K chloride
%K pentalene Derivatives
%K aryl
%K yield
%K construction
%K Aryl
%K application
%K closure
%K challenge
%K Ketone
%K Dibenzo
%K carbocycle
%K ketone
%K tandem
%X The
rapid construction of three-dimensional fused carbocycles is
a key challenge in synthetic chemistry. Herein, an unprecedented and
practical tandem Nazarov/oxidative umpolung 4π-ring closure
of readily available 1,2-allenyl aryl ketones mediated by iron(III)
chloride has been developed, furnishing a new family of indanone-fused
molecular architectures in moderate to excellent yields. The indanone-containing
blocks can be efficiently converted to unsymmetrical dibenzo[a,e]pentalenes. Significantly, divergent
synthetic applications have been achieved to provide densely functionalized
polycyclic arrays.
%I ACS Publications