Enantiomers of Single Chirality Nanotube as Chiral
Recognition Interface for Enhanced Electrochemical Chiral Analysis
Chunling Pu
Yunxia Xu
Qi Liu
Anwei Zhu
Guoyue Shi
10.1021/acs.analchem.8b05336.s001
https://acs.figshare.com/articles/journal_contribution/Enantiomers_of_Single_Chirality_Nanotube_as_Chiral_Recognition_Interface_for_Enhanced_Electrochemical_Chiral_Analysis/7646792
Although
separation of single-walled carbon nanotubes (SWCNTs)
according to their helicity and handedness has been attracting tremendous
interest recently, exploration of the left- and right-handed SWCNT
enantiomers (defined as “M” and “P”) to
chiral sensing still remains in the early stage. Here we presented
a new electrochemical sensor for chiral discrimination, which for
the first time amplified the chiral selection on the electrode surface
based on the left- or right-handed semiconducting SWCNT enantiomers
with (6,5)-enriched chirality. The enantioselectivity was demonstrated
by different peak current response to analyte enantiomers, observed
in differential pulse voltammogram (DPV). Chiral distinguishing might
be a result of the formation of an efficient chiral nanospace originating
from the high purity of single enantiomer of (6,5) SWCNT. The obtained
chiral electrodes were also applied to determine the enantiomeric
excess (ee) of DOPA. There was a good linear relationship between
DPV peak currents and % ee of l-DOPA. This study is the first
example showing how the structure of chiral SWCNTs influences electrochemical
chiral recognition.
2019-01-15 00:00:00
semiconducting SWCNT enantiomers
Chiral Recognition Interface
chiral SWCNTs influences electrochemical chiral recognition
Single Chirality Nanotube
single-walled carbon nanotubes
pulse voltammogram
Enhanced Electrochemical Chiral Analysis
electrochemical sensor
chiral nanospace
DOPA
electrode surface
SWCNT enantiomers
chiral electrodes
DPV peak currents
analyte enantiomers
chiral selection
chiral discrimination