10.1021/acs.jafc.8b05479.s001
Yatai Li
Yatai
Li
Wei Guo
Wei
Guo
Zhaochu Hu
Zhaochu
Hu
Lanlan Jin
Lanlan
Jin
Shenghong Hu
Shenghong
Hu
Qinghai Guo
Qinghai
Guo
Method Development for Direct Multielement Quantification
by LA-ICP-MS in Food Samples
American Chemical Society
2018
Analysis results
agarose-gel standards
reference materials
gel homogeneity
rubber sample supporter
novel calibration strategy
plasma mass spectrometry
Food Samples
Direct Multielement Quantification
gel standards
Method Development
LOD
analysis throughput
Aqueous solutions
analyte
LA-ICP-MS
CRM
2018-12-28 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Method_Development_for_Direct_Multielement_Quantification_by_LA-ICP-MS_in_Food_Samples/7575494
A novel calibration strategy for
the accurate determination of
essential and toxic elements in both plant-based and animal-based
foods was developed by synthesizing spiked agarose gels as matrix-matched
external standards and carbon as the internal standard (IS). Aqueous
solutions of agarose (4%, m/v) with defined amounts of the analytes
were cast on a mold and then dried to form the agarose-gel standards.
The spatial distributions of the analytes in the gel were examined
using surface- and depth-mapping laser ablation–inductively
coupled plasma mass spectrometry (LA-ICP-MS) protocols, and the gel
homogeneity was found to be excellent (i.e., relative standard derivation
<10%). Recovery of the 19 spiked elements in the gel standards
was in the range of 86.9–94.7%. The limits of detection (LODs)
ranged from 0.0005 (Rb) to 33.7 μg g<sup>–1</sup> (S).
Analysis results were in good agreement with certified values for
various certified reference materials (CRMs). Furthermore, a porous
rubber sample supporter was developed to improve the analysis throughput
by about 3-fold.