%0 Journal Article
%A Li, Wei
%A He, Juan
%A Feng, Tao
%A Yang, Hui-Xiang
%A Ai, Hong-Lian
%A Li, Zheng-Hui
%A Liu, Ji-Kai
%D 2018
%T Antroalbocin A, an Antibacterial Sesquiterpenoid from
Higher Fungus Antrodiella albocinnamomea
%U https://acs.figshare.com/articles/journal_contribution/Antroalbocin_A_an_Antibacterial_Sesquiterpenoid_from_Higher_Fungus_i_Antrodiella_albocinnamomea_i_/7398908
%R 10.1021/acs.orglett.8b03595.s001
%2 https://acs.figshare.com/ndownloader/files/13686779
%K Compound 1
%K Staphylococcus aureus
%K biosynthetic pathway
%K culture
%K MIC value
%K Antibacterial Sesquiterpenoid
%K Fungus Antrodiella albocinnamomea Antroalbocin
%K 169 μ M
%K bridged tricyclic system
%K fungus Antrodiella albocinnamomea
%K sesquiterpenoid
%K Basidiomycota
%K configuration
%K spectroscopic methods
%K single-crystal X-ray diffraction
%X Antroalbocin A (1), a sesquiterpenoid possessing a
bridged tricyclic system, was isolated from cultures of the higher
fungus Antrodiella albocinnamomea (Basidiomycota).
The structure with the absolute configuration was determined by extensive
spectroscopic methods and single-crystal X-ray diffraction. A plausible
biosynthetic pathway for 1 was proposed. Compound 1 was found to inhibit Staphylococcus aureus with an MIC value of 169 μM.
%I ACS Publications