Zhu, Changyou Huang, Manling Lan, Jialing Chung, Lung Wa Li, Xin Xie, Xiaojiang Colorimetric Calcium Probe with Comparison to an Ion-Selective Optode Design strategies for small molecular probes lay the foundation of numerous synthetic chemosensors. A water-soluble colorimetric calcium molecular probe inspired by the ionophore-based ion-selective optode is presented here with a tunable detection range (around micromolar at pH 7). The binding of Ca<sup>2+</sup> resulted in the deprotonation of the probe and thus a significant spectral change, mimicking the ion-exchange process in ion-selective optodes. The 1:1 exchange between Ca<sup>2+</sup> and H<sup>+</sup> was confirmed with Job’s plot. Computational studies revealed possible monomer and dimer forms of the probe–Ca<sup>2+</sup> complexes. probe;colorimetric calcium;ion-exchange process;dimer forms;Computational studies;tunable detection range;Ion-Selective Optode Design strategies;ion-selective optodes;Colorimetric Calcium Probe;ionophore-based ion-selective optode 2018-10-03
    https://acs.figshare.com/articles/journal_contribution/Colorimetric_Calcium_Probe_with_Comparison_to_an_Ion-Selective_Optode/7159646
10.1021/acsomega.8b01813.s001