10.1021/acsomega.8b01813.s001
Changyou Zhu
Changyou
Zhu
Manling Huang
Manling
Huang
Jialing Lan
Jialing
Lan
Lung Wa Chung
Lung Wa
Chung
Xin Li
Xin
Li
Xiaojiang Xie
Xiaojiang
Xie
Colorimetric Calcium Probe with Comparison to an Ion-Selective
Optode
American Chemical Society
2018
probe
colorimetric calcium
ion-exchange process
dimer forms
Computational studies
tunable detection range
Ion-Selective Optode Design strategies
ion-selective optodes
Colorimetric Calcium Probe
ionophore-based ion-selective optode
2018-10-03 08:13:36
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Colorimetric_Calcium_Probe_with_Comparison_to_an_Ion-Selective_Optode/7159646
Design strategies for small molecular
probes lay the foundation
of numerous synthetic chemosensors. A water-soluble colorimetric calcium
molecular probe inspired by the ionophore-based ion-selective optode
is presented here with a tunable detection range (around micromolar
at pH 7). The binding of Ca<sup>2+</sup> resulted in the deprotonation
of the probe and thus a significant spectral change, mimicking the
ion-exchange process in ion-selective optodes. The 1:1 exchange between
Ca<sup>2+</sup> and H<sup>+</sup> was confirmed with Job’s
plot. Computational studies revealed possible monomer and dimer forms
of the probe–Ca<sup>2+</sup> complexes.