%0 Journal Article
%A Ming, Jialin
%A Hayashi, Tamio
%D 2018
%T Rhodium-Catalyzed Arylzincation of Alkynes: Ligand
Control of 1,4‑Migration Selectivity
%U https://acs.figshare.com/articles/journal_contribution/Rhodium-Catalyzed_Arylzincation_of_Alkynes_Ligand_Control_of_1_4_Migration_Selectivity/7111202
%R 10.1021/acs.orglett.8b02668.s001
%2 https://acs.figshare.com/ndownloader/files/13086413
%K rhodium complexes
%K arylzinc reagents ArZnCl 1
%K zinc chloride
%K migration
%K ligand
%K presence
%K Rhodium-Catalyzed Arylzincation
%K binap
%K Alkyne
%K 2- arylalkenylzinc species 3
%K Ligands cod
%K selectivity
%K Ligand Control
%K Selectivity
%K ortho
%K Migration
%K alkynes 2
%K alkenylarylzinc species 4
%K latter
%X The addition of arylzinc
reagents ArZnCl 1 to alkynes 2 was found
to be catalyzed by rhodium complexes in the presence
of a catalytic amount of zinc chloride. The selectivity in giving
2-arylalkenylzinc species 3 or ortho-alkenylarylzinc species 4, the latter of which is generated
through 1,4-Rh migration from alkenyl to aryl in the catalytic cycle,
is controlled by the ligands on rhodium. Ligands cod and binap gave 3 and 4, respectively, with high selectivity.
%I ACS Publications