10.1021/acscatal.8b02661.s002 Hai-Jie Song Hai-Jie Song Wei-Tao Jiang Wei-Tao Jiang Qiao-Lan Zhou Qiao-Lan Zhou Meng-Yu Xu Meng-Yu Xu Bin Xiao Bin Xiao Structure-Modified Germatranes for Pd-Catalyzed Biaryl Synthesis American Chemical Society 2018 germatrane nucleophilic fragments Pd-catalyzed germylation Ge-containing nucleophiles Grignard reagents aryl halides Structure-Modified Germatranes GeO 2 cross-coupling reactivity Pd-Catalyzed Biaryl Synthesis Germanium 2018-09-04 00:00:00 Dataset https://acs.figshare.com/articles/dataset/Structure-Modified_Germatranes_for_Pd-Catalyzed_Biaryl_Synthesis/7059068 Germanium, a member of 14th group that falls between Si and Sn, has remained considerably ignored as a nucleophile for a long time. Compared with other forms of Ge-containing nucleophiles, germatranes are structure-defined, easily accessible, and stabilized nucleophilic fragments, but they fail to meet the need of high reactivity and facile introducing to organics. Herein, we report a modified structure of germatranes, whose cross-coupling reactivity is greatly improved. The structure can be easily constructed from inexpensive industrial GeO<sub>2</sub>, and corresponding <b><i>Ge</i></b>-Cl and <b><i>Ge</i></b>-H can also be obtained after facile transformations. Moreover, Ar-<b><i>Ge</i></b> can be effectively synthesized either from Grignard reagents or Pd-catalyzed germylation of aryl halides.