Shi, Zhenyu Hammond, Gerald B. Xu, Bo Faster and Greener Chemical Reaction Workup Using Silicone Elastomer-Coated Glass Powders We have developed a substantially faster and greener technique for routine chemical reaction workups. We use silicone elastomer-coated glass powder (“FastWoRX”) as an absorbent to extract organic products from a quenched aqueous reaction mixture. After filtration, FastWoRX powder loaded with organic products can serve as a convenient input for flash chromatographic separations. With this technique, tedious and solvent-consuming liquid–liquid extractions are replaced by a simple filtration. Use of FastWoRX reduces solvent use and the <i>E</i>-factor by up to an order of magnitude compared to traditional liquid–liquid extraction-based workup. FastWoRX powder;reaction mixture;filtration;technique;chemical reaction workups;Silicone Elastomer-Coated Glass Powders;Chemical Reaction Workup 2018-06-21
    https://acs.figshare.com/articles/journal_contribution/Faster_and_Greener_Chemical_Reaction_Workup_Using_Silicone_Elastomer-Coated_Glass_Powders/6633914
10.1021/acsomega.8b00966.s001