Faster and Greener Chemical Reaction Workup Using
Silicone Elastomer-Coated Glass Powders
Zhenyu Shi
Gerald B. Hammond
Bo Xu
10.1021/acsomega.8b00966.s001
https://acs.figshare.com/articles/journal_contribution/Faster_and_Greener_Chemical_Reaction_Workup_Using_Silicone_Elastomer-Coated_Glass_Powders/6633914
We
have developed a substantially faster and greener technique
for routine chemical reaction workups. We use silicone elastomer-coated
glass powder (“FastWoRX”) as an absorbent to extract
organic products from a quenched aqueous reaction mixture. After filtration,
FastWoRX powder loaded with organic products can serve as a convenient
input for flash chromatographic separations. With this technique,
tedious and solvent-consuming liquid–liquid extractions are
replaced by a simple filtration. Use of FastWoRX reduces solvent use
and the <i>E</i>-factor by up to an order of magnitude compared
to traditional liquid–liquid extraction-based workup.
2018-06-21 11:33:40
FastWoRX powder
reaction mixture
filtration
technique
chemical reaction workups
Silicone Elastomer-Coated Glass Powders
Chemical Reaction Workup