%0 Generic %A Uemura, Naohiro %A Toyoda, Seiya %A Ishikawa, Hiroki %A Yoshida, Yasushi %A Mino, Takashi %A Kasashima, Yoshio %A Sakamoto, Masami %D 2018 %T Asymmetric Diels–Alder Reaction Involving Dynamic Enantioselective Crystallization %U https://acs.figshare.com/articles/dataset/Asymmetric_Diels_Alder_Reaction_Involving_Dynamic_Enantioselective_Crystallization/6483977 %R 10.1021/acs.joc.8b01273.s003 %2 https://acs.figshare.com/ndownloader/files/11922026 %K adduct %K reaction mixture %K glass beads %K attrition-enhanced deracemization %K Asymmetric %K Diel %K conglomerate crystal %K exo %K hexane solution %K prochiral 2- methylfuran %K achiral conditions %X Asymmetric Diels–Alder reaction was achieved under achiral conditions. Reaction of prochiral 2-methylfuran and N-phenylmaleimide in heptane or hexane solution at 80 °C efficiently gave a conglomerate crystal of exo-type Diels–Alder adduct selectively, and continuous suspension of the reaction mixture with glass beads promoted attrition-enhanced deracemization, leading to an optically active exo-adduct in 90% ee. %I ACS Publications