%0 Journal Article
%A Zhang, Ming-Zhong
%A Luo, Na
%A Long, Rui-Yang
%A Gou, Xian-Tao
%A Shi, Wen-Bing
%A He, Shu-Hua
%A Jiang, Yong
%A Chen, Jin-Yang
%A Chen, Tieqiao
%D 2018
%T Transition-Metal-Free
Oxidative Aminooxyarylation
of Alkenes: Annulations toward Aminooxylated Oxindoles
%U https://acs.figshare.com/articles/journal_contribution/Transition-Metal-Free_Oxidative_Aminooxyarylation_of_Alkenes_Annulations_toward_Aminooxylated_Oxindoles/5852778
%R 10.1021/acs.joc.7b02740.s001
%2 https://acs.figshare.com/ndownloader/files/10387365
%K reaction conditions
%K Transition-Metal-Free Oxidative Aminooxyarylation
%K NHPI
%K aminooxylated
%K bond
%X An efficient oxidative aminooxyarylation
of alkenes under a transition-metal-free
condition was described. Under the reaction conditions, N-hydroxyphthalimide (NHPI) reacted readily with N-arylacrylamides to produce cyclic products via a radical C–H
functionalization process, achieving both C–O and C–C
bonds formation in one pot. This reaction provided a facile access
to the valuable aminooxylated oxindoles. The benzylic and α-methylene
C(sp3)-H bonds were also aminooxylated under the reaction
conditions.
%I ACS Publications