Jiang, Yang-Jie Zhang, Gao-Peng Huang, Jian-Qiang Chen, Di Ding, Chang-Hua Hou, Xue-Long Palladium-Catalyzed Asymmetric Allylic Alkylation of Alkyl-Substituted Allyl Reagents with Acyclic Amides A wide range of alkyl-substituted allyl reagents, as well as nonstabilized carbon nucleophiles, was successfully used for the first time in the palladium-catalyzed asymmetric allylic alkylation reaction, affording the corresponding allylic alkylated products in high yields with high enantioselectivities. The usefulness of the protocol has been demonstrated by the enantioselective synthesis of an important chiral building block and enantiomer of Dubiusamine A. chiral building block;usefulness;Dubiusamine;Acyclic Amides;allylic alkylated products;Alkyl-Substituted Allyl Reagents;enantiomer;enantioselective synthesis;enantioselectivitie;allylic alkylation reaction;palladium-catalyzed;Palladium-Catalyzed Asymmetric Allylic Alkylation;nonstabilized carbon nucleophiles;alkyl-substituted allyl reagents;yield 2017-10-18
    https://acs.figshare.com/articles/journal_contribution/Palladium-Catalyzed_Asymmetric_Allylic_Alkylation_of_Alkyl-Substituted_Allyl_Reagents_with_Acyclic_Amides/5510185
10.1021/acs.orglett.7b02927.s001