Cobalt-Catalyzed Silylcarbonylation of Unactivated Secondary Alkyl Tosylates at Low Pressure Joan E. Roque Peña Erik J. Alexanian 10.1021/acs.orglett.7b02117.s001 https://acs.figshare.com/articles/journal_contribution/Cobalt-Catalyzed_Silylcarbonylation_of_Unactivated_Secondary_Alkyl_Tosylates_at_Low_Pressure/5305366 A catalytic preparation of silyl enol ethers from unactivated secondary alkyl tosylates is reported. An inexpensive cobalt catalyst is used under mild conditions with low pressures of carbon monoxide. Nucleophilic, anionic cobalt carbonyls facilitate the catalytic activation of a range of alkyl tosylates. The silylcarbonylation offers a practical approach to synthetically valuable silyl enol ethers from simple starting materials. 2017-08-11 18:35:48 Nucleophilic Cobalt-Catalyzed carbonyl monoxide silyl enol ethers synthetically Tosylate Silylcarbonylation approach Unactivated alkyl tosylates Alkyl activation material catalyst silylcarbonylation cobalt unactivated preparation