%0 Journal Article %A Zhang, Lei %A Lu, Hong %A Xu, Guo-Qiang %A Wang, Zhu-Yin %A Xu, Peng-Fei %D 2017 %T PPh3 Mediated Reductive Annulation Reaction between Isatins and Electron Deficient Dienes to Construct Spirooxindole Compounds %U https://acs.figshare.com/articles/journal_contribution/PPh_sub_3_sub_Mediated_Reductive_Annulation_Reaction_between_Isatins_and_Electron_Deficient_Dienes_to_Construct_Spirooxindole_Compounds/5025020 %R 10.1021/acs.joc.7b00595.s001 %2 https://acs.figshare.com/ndownloader/files/8483342 %K alternative method %K Lewis acid %K PPh 3 %K spirocyclopentenyl oxindole compounds %K reductive annulation reaction %K PPh 3 Mediated Reductive Annulation Reaction %K role %K synthesis %K three-membered all-carbon spirooxindole compounds %K Spirooxindole Compounds %K Lithium chloride %K dicyano %K -2-methylenebut %K isatin %K Electron Deficient Dienes %K Isatin %X A PPh3 mediated reductive annulation reaction between isatins and 4,4-dicyano-2-methylenebut-3-enoates was developed. The reaction provided an alternative method for constructing five- and three-membered all-carbon spirooxindole compounds. Lithium chloride as a Lewis acid played a key role in the synthesis of spirocyclopentenyl oxindole compounds. %I ACS Publications