10.1021/acs.joc.7b00595.s001
Lei Zhang
Lei
Zhang
Hong Lu
Hong
Lu
Guo-Qiang Xu
Guo-Qiang
Xu
Zhu-Yin Wang
Zhu-Yin
Wang
Peng-Fei Xu
Peng-Fei
Xu
PPh<sub>3</sub> Mediated
Reductive Annulation Reaction
between Isatins and Electron Deficient Dienes to Construct Spirooxindole
Compounds
American Chemical Society
2017
alternative method
Lewis acid
PPh 3
spirocyclopentenyl oxindole compounds
reductive annulation reaction
PPh 3 Mediated Reductive Annulation Reaction
role
synthesis
three-membered all-carbon spirooxindole compounds
Spirooxindole Compounds
Lithium chloride
dicyano
-2-methylenebut
isatin
Electron Deficient Dienes
Isatin
2017-05-15 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/PPh_sub_3_sub_Mediated_Reductive_Annulation_Reaction_between_Isatins_and_Electron_Deficient_Dienes_to_Construct_Spirooxindole_Compounds/5025020
A PPh<sub>3</sub> mediated reductive annulation reaction between
isatins and 4,4-dicyano-2-methylenebut-3-enoates was developed. The
reaction provided an alternative method for constructing five- and
three-membered all-carbon spirooxindole compounds. Lithium chloride
as a Lewis acid played a key role in the synthesis of spirocyclopentenyl
oxindole compounds.