10.1021/acs.joc.7b00595.s001 Lei Zhang Lei Zhang Hong Lu Hong Lu Guo-Qiang Xu Guo-Qiang Xu Zhu-Yin Wang Zhu-Yin Wang Peng-Fei Xu Peng-Fei Xu PPh<sub>3</sub> Mediated Reductive Annulation Reaction between Isatins and Electron Deficient Dienes to Construct Spirooxindole Compounds American Chemical Society 2017 alternative method Lewis acid PPh 3 spirocyclopentenyl oxindole compounds reductive annulation reaction PPh 3 Mediated Reductive Annulation Reaction role synthesis three-membered all-carbon spirooxindole compounds Spirooxindole Compounds Lithium chloride dicyano -2-methylenebut isatin Electron Deficient Dienes Isatin 2017-05-15 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/PPh_sub_3_sub_Mediated_Reductive_Annulation_Reaction_between_Isatins_and_Electron_Deficient_Dienes_to_Construct_Spirooxindole_Compounds/5025020 A PPh<sub>3</sub> mediated reductive annulation reaction between isatins and 4,4-dicyano-2-methylenebut-3-enoates was developed. The reaction provided an alternative method for constructing five- and three-membered all-carbon spirooxindole compounds. Lithium chloride as a Lewis acid played a key role in the synthesis of spirocyclopentenyl oxindole compounds.