%0 Generic %A Zheng, Kai-Lu %A You, Min-Qi %A Shu, Wen-Ming %A Wu, Yan-Dong %A Wu, An-Xin %D 2017 %T Acid-Mediated Intermolecular [3 + 2] Cycloaddition toward Pyrrolo[2,1‑a]isoquinolines: Total Synthesis of the Lamellarin Core and Lamellarin G Trimethyl Ether %U https://acs.figshare.com/articles/dataset/Acid-Mediated_Intermolecular_3_2_Cycloaddition_toward_Pyrrolo_2_1_i_a_i_isoquinolines_Total_Synthesis_of_the_Lamellarin_Core_and_Lamellarin_G_Trimethyl_Ether/4888370 %R 10.1021/acs.orglett.7b00769.s002 %2 https://acs.figshare.com/ndownloader/files/8213516 %K Suzuki %K novel one-pot reaction %K lamellarin G trimethyl ether %K lamellarin core %K cross-coupling %K Lamellarin Core %K pyrrolo %K nitrovinyl %K electrophilic substitution %K synthesis %K Acid-Mediated %K Lamellarin G Trimethyl Ether %K strategy %K 1- dearyllamellarin core %K isoquinoline %K palladium-catalyzed %K Total Synthesis %K Cycloaddition %K azomethine ylides %K Pyrrolo %K Intermolecular %X A novel one-pot reaction has been developed for the efficient synthesis of pyrrolo­[2,1-a]­isoquinolines and 1-dearyllamellarin core from (E)-(2-nitrovinyl)­benzenes and azomethine ylides generated in situ. This strategy provides a concise total synthesis of the lamellarin core and lamellarin G trimethyl ether using electrophilic substitution and palladium-catalyzed Suzuki–Miyaura cross-coupling reactions. %I ACS Publications