%0 Generic
%A Zheng, Kai-Lu
%A You, Min-Qi
%A Shu, Wen-Ming
%A Wu, Yan-Dong
%A Wu, An-Xin
%D 2017
%T Acid-Mediated Intermolecular [3 + 2] Cycloaddition
toward Pyrrolo[2,1‑a]isoquinolines: Total
Synthesis of the Lamellarin Core and Lamellarin G Trimethyl Ether
%U https://acs.figshare.com/articles/dataset/Acid-Mediated_Intermolecular_3_2_Cycloaddition_toward_Pyrrolo_2_1_i_a_i_isoquinolines_Total_Synthesis_of_the_Lamellarin_Core_and_Lamellarin_G_Trimethyl_Ether/4888370
%R 10.1021/acs.orglett.7b00769.s002
%2 https://acs.figshare.com/ndownloader/files/8213516
%K Suzuki
%K novel one-pot reaction
%K lamellarin G trimethyl ether
%K lamellarin core
%K cross-coupling
%K Lamellarin Core
%K pyrrolo
%K nitrovinyl
%K electrophilic substitution
%K synthesis
%K Acid-Mediated
%K Lamellarin G Trimethyl Ether
%K strategy
%K 1- dearyllamellarin core
%K isoquinoline
%K palladium-catalyzed
%K Total Synthesis
%K Cycloaddition
%K azomethine ylides
%K Pyrrolo
%K Intermolecular
%X A novel one-pot reaction
has been developed for the efficient synthesis
of pyrrolo[2,1-a]isoquinolines and 1-dearyllamellarin
core from (E)-(2-nitrovinyl)benzenes and azomethine
ylides generated in situ. This strategy provides
a concise total synthesis of the lamellarin core and lamellarin G
trimethyl ether using electrophilic substitution and palladium-catalyzed
Suzuki–Miyaura cross-coupling reactions.
%I ACS Publications