%0 Journal Article %A Wang, Chunxia %A Zhang, Luoqiang %A You, Jingsong %D 2017 %T Nickel-Catalyzed Aminoxylation of Inert Aliphatic C(sp3)–H Bonds with Stable Nitroxyl Radicals under Air: One-Pot Route to α‑Formyl Acid Derivatives %U https://acs.figshare.com/articles/journal_contribution/Nickel-Catalyzed_Aminoxylation_of_Inert_Aliphatic_C_sp_sup_3_sup_H_Bonds_with_Stable_Nitroxyl_Radicals_under_Air_One-Pot_Route_to_Formyl_Acid_Derivatives/4784491 %R 10.1021/acs.orglett.7b00479.s001 %2 https://acs.figshare.com/ndownloader/files/7860424 %K Stable Nitroxyl Radicals %K evidence %K α- formyl acid derivatives %K Derivatives Nickel-catalyzed aminoxylation %K Inert %K one-pot approach %K Nickel-Catalyzed Aminoxylation %K alkoxyamine derivatives %K oxidative addition %K One-Pot Route %K aminoxylation process %K Formyl %K nitroxyl %K cyclometallic %K Bond %K unactivated %K transition-metal-catalyzed functionalization %K Aliphatic %K reaction-mechanism study %K bond %X Nickel-catalyzed aminoxylation of an unactivated C­(sp3)–H bond with a stable nitroxyl radical has been accomplished for the first time to offer various N-alkoxyamine derivatives, which further enables a one-pot approach to α-formyl acid derivatives. The aminoxylation process reported also provides direct evidence for the oxidative addition of a cyclometallic intermediate with a free radical, which is helpful for the reaction-mechanism study in transition-metal-catalyzed functionalization of inert C­(sp3)–H bonds. %I ACS Publications