10.1021/acs.jafc.7b00051.s001
Kailin Deng
Kailin
Deng
Wan Chan
Wan
Chan
Development of a
QuEChERS-Based Method for Determination of Carcinogenic 2‑Nitrofluorene
and 1‑Nitropyrene in Rice Grains and Vegetables: A Comparative
Study with Benzo[<i>a</i>]pyrene
American Chemical Society
2017
food samples
nitro-PAHs exposure
Previous studies
pyrene Nitrated polycyclic
Rice Grains
2- nitrofluorene
food contaminants
surveillance data
vegetable samples
1- nitropyrene
rice grains
QuEChERS-Based Method
Dietary exposure risk
Comparative Study
PAH exposure
formation mechanisms
Hong Kong citizens
2017-02-20 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Development_of_a_QuEChERS-Based_Method_for_Determination_of_Carcinogenic_2_Nitrofluorene_and_1_Nitropyrene_in_Rice_Grains_and_Vegetables_A_Comparative_Study_with_Benzo_i_a_i_pyrene/4688320
Nitrated polycyclic
aromatic hydrocarbons (nitro-PAHs) are ubiquitous environmental pollutants
attracting increasing attention because of their potent mutagenicity
to humans. Previous studies of nitro-PAHs focused on investigating
their formation mechanisms and detecting them in atmospheric environment;
however, few studies have reported their occurrence in food samples,
and regulations on nitro-PAHs are still lacking. We report in this
study the development and application of a quick, easy, cheap, effective,
rugged, and safe (QuEChERS) method for determination of nitro-PAHs
in rice and vegetable samples. Analysis of the collected samples by
the validated method revealed 1-nitropyrene and 2-nitrofluorene were
widespread food contaminants. A comparative study with benzo[<i>a</i>]pyrene, the commonly used marker for PAH exposure, showed
that carcinogenic nitro-PAHs existed in rice and vegetables at similar
concentrations. Dietary exposure risk, which was estimated based on
the surveillance data, suggested 3.28–5.03 ng/kg/day of nitro-PAHs
exposure for Hong Kong citizens from rice grains and vegetables.