Zhang, Min Liu, Jimei Chen, Ridao Zhao, Jinlian Xie, Kebo Chen, Dawei Feng, Keping Dai, Jungui Two Furanharzianones with 4/7/5/6/5 Ring System from Microbial Transformation of Harzianone Furanharzianones A and B (<b>2</b> and <b>3</b>), two new harziane-type diterpenoids with a tetrahydrofuran and unusual 4/7/5/6/5 ring system, were obtained from the microbial transformation of harzianone (<b>1</b>) by a bacterial strain <i>Bacillus</i> sp. IMM-006. The structures, including the stereochemistry, of the two new compounds were elucidated by extensive spectroscopic analysis. The absolute configuration of <b>2</b> was unambiguously determined by single-crystal X-ray diffraction. In addition, a plausible bioconversion pathway was proposed. bioconversion pathway;spectroscopic analysis;configuration;Microbial Transformation;IMM -006.;stereochemistry;tetrahydrofuran;strain Bacillus sp;compound;Harzianone Furanharzianones;transformation;harziane-type diterpenoids;single-crystal X-ray diffraction 2017-02-20
    https://acs.figshare.com/articles/dataset/Two_Furanharzianones_with_4_7_5_6_5_Ring_System_from_Microbial_Transformation_of_Harzianone/4669048
10.1021/acs.orglett.7b00204.s002