Enantioselective Synthesis of [6]Carbohelicenes Elisa González-Fernández Leo D. M. Nicholls Lukas D. Schaaf Christophe Farès Christian W. Lehmann Manuel Alcarazo 10.1021/jacs.6b12443.s006 https://acs.figshare.com/articles/dataset/Enantioselective_Synthesis_of_6_Carbohelicenes/4579504 The use of α-cationic phosphonites derived from TADDOL as ancillary ligands has allowed a highly regio- and enantioselective synthesis of substituted [6]­carbohelicenes by sequential Au-catalyzed intramolecular hydroarylation of diynes. Key for these results is the modular structure of these new ligands, and the enhanced reactivity that they impart to Au­(I)-centers after coordination. 2017-01-23 19:23:12 coordination ligand Carbohelicene reactivity α- cationic phosphonites enantioselective synthesis TADDOL diyne carbohelicene regio sequential Au-catalyzed intramolecular hydroarylation Enantioselective Synthesis