%0 Journal Article %A Weidner, Victoria L. %A Barger, Christopher J. %A Delferro, Massimiliano %A Lohr, Tracy L. %A Marks, Tobin J. %D 2017 %T Rapid, Mild, and Selective Ketone and Aldehyde Hydroboration/Reduction Mediated by a Simple Lanthanide Catalyst %U https://acs.figshare.com/articles/journal_contribution/Rapid_Mild_and_Selective_Ketone_and_Aldehyde_Hydroboration_Reduction_Mediated_by_a_Simple_Lanthanide_Catalyst/4547275 %R 10.1021/acscatal.6b03332.s001 %2 https://acs.figshare.com/ndownloader/files/7364845 %K 5 min %K La NTMS %K Selective Ketone %K group compatibility %K nitro groups %K hydroboration %K catalyst %K Simple Lanthanide Catalyst Rapid %X Rapid, clean hydroboration of ketones and aldehydes with HBpin is achieved using the homoleptic rare-earth catalyst La­[N­(SiMe3)2]3 (LaNTMS). The reaction employs low catalyst loadings (0.01–1 mol % LaNTMS), proceeds rapidly (>99% in 5 min) at 25 °C, and is moderately air-tolerant. Additionally, this hydroboration has good functional group compatibility, including halides, nitro groups, and nitriles, and is exclusively carbonyl-selective in the presence of alkenes and alkynes. %I ACS Publications