10.1021/acs.inorgchem.6b02589.s001 Xiu-Ying Zheng Xiu-Ying Zheng Jun-Bo Peng Jun-Bo Peng M. M. Varuni S. Livera M. M. Varuni S. Livera Yun Luo Yun Luo Ya-Yun Wang Ya-Yun Wang Xiang-Jian Kong Xiang-Jian Kong La-Sheng Long La-Sheng Long Zhiping Zheng Zhiping Zheng Lan-Sun Zheng Lan-Sun Zheng Selective Formation of Chromogen I from <i>N</i>‑Acetyl‑d‑glucosamine upon Lanthanide Coordination American Chemical Society 2016 nanostructured 54- metal cagelike assembly nonanuclear lanthanide complexes hex -2-enofuranose OH Free Chromogen deprotonated chiral ligand Chromogen H 2 O Selective Formation solution stability dehydrating GlcNAc Ln cluster LH Lanthanide Coordination Mass spectroscopic studies 2016-12-09 21:29:36 Journal contribution https://acs.figshare.com/articles/journal_contribution/Selective_Formation_of_Chromogen_I_from_i_N_i_Acetyl_d_glucosamine_upon_Lanthanide_Coordination/4307708 We report two nonanuclear lanthanide complexes, [Ln<sub>9</sub>(μ<sub>4</sub>-O)­(μ<sub>3</sub>-OH)<sub>8</sub>(LH)<sub>4</sub>(OAc)<sub>4</sub>(H<sub>2</sub>O)<sub>12</sub>]·5ClO<sub>4</sub>·24H<sub>2</sub>O (Ln = Gd, <b>1</b>; Dy, <b>2</b>), where LH<sup>2–</sup> is the doubly deprotonated chiral ligand Chromogen I (2-acetamido-2,3-dideoxy-D-<i>erythro</i>-hex-2-enofuranose), one of the many products from the dehydration of <i>N</i>-acetyl-D-glucosamine (GlcNAc). Mass spectroscopic studies established the solution stability of these clusters. Through hydrogen bonding, the cluster complex self-organizes into a nanostructured 54-metal cagelike assembly featuring six of its units occupying the vertices of an octahedron. Free Chromogen I can be obtained in pure form and high yield by a straightforward workup of the cluster complex. This is the first report of dehydrating GlcNAc without the need of a catalyst or forcing conditions.