Dimericbiscognienyne A: A Meroterpenoid Dimer from <i>Biscogniauxia</i> sp. with New Skeleton and Its Activity Huan Zhao Guo-Dong Chen Jian Zou Rong-Rong He Sheng-Ying Qin Dan Hu Guo-Qiang Li Liang-Dong Guo Xin-Sheng Yao Hao Gao 10.1021/acs.orglett.6b03264.s003 https://acs.figshare.com/articles/dataset/Dimericbiscognienyne_A_A_Meroterpenoid_Dimer_from_i_Biscogniauxia_i_sp_with_New_Skeleton_and_Its_Activity/4299779 Dimericbiscognienyne A (<b>1</b>), an unusual diisoprenyl-cyclohexene-type meroterpenoid dimer, was isolated from <i>Biscogniauxia</i> sp. together with three new monomeric diisoprenyl-cyclohexene-type meroterpenoids (<b>2</b>–<b>4</b>) and one new isoprenyl-benzoic acid-type meroterpenoid (<b>5</b>). All structures were determined by extensive NMR spectroscopic methods, quantum chemical calculations, chemical derivatization, and X-ray crystallography. The formation of <b>1</b> is related to a unique intermolecular redox coupling Diels–Alder adduct reaction. Their cytotoxicities and short-term memory enhancement activities against Alzheimer’s disease were assessed. 2016-12-09 12:20:57 quantum chemical calculations Dimericbiscognienyne monomeric diisoprenyl-cyclohexene-type meroterpenoids NMR spectroscopic methods Biscogniauxia sp memory enhancement activities diisoprenyl-cyclohexene-type meroterpenoid dimer isoprenyl-benzoic acid-type meroterpenoid