Zhao, Huan Chen, Guo-Dong Zou, Jian He, Rong-Rong Qin, Sheng-Ying Hu, Dan Li, Guo-Qiang Guo, Liang-Dong Yao, Xin-Sheng Gao, Hao Dimericbiscognienyne A: A Meroterpenoid Dimer from <i>Biscogniauxia</i> sp. with New Skeleton and Its Activity Dimericbiscognienyne A (<b>1</b>), an unusual diisoprenyl-cyclohexene-type meroterpenoid dimer, was isolated from <i>Biscogniauxia</i> sp. together with three new monomeric diisoprenyl-cyclohexene-type meroterpenoids (<b>2</b>–<b>4</b>) and one new isoprenyl-benzoic acid-type meroterpenoid (<b>5</b>). All structures were determined by extensive NMR spectroscopic methods, quantum chemical calculations, chemical derivatization, and X-ray crystallography. The formation of <b>1</b> is related to a unique intermolecular redox coupling Diels–Alder adduct reaction. Their cytotoxicities and short-term memory enhancement activities against Alzheimer’s disease were assessed. quantum chemical calculations;Dimericbiscognienyne;monomeric diisoprenyl-cyclohexene-type meroterpenoids;NMR spectroscopic methods;Biscogniauxia sp;memory enhancement activities;diisoprenyl-cyclohexene-type meroterpenoid dimer;isoprenyl-benzoic acid-type meroterpenoid 2016-12-09
    https://acs.figshare.com/articles/dataset/Dimericbiscognienyne_A_A_Meroterpenoid_Dimer_from_i_Biscogniauxia_i_sp_with_New_Skeleton_and_Its_Activity/4299776
10.1021/acs.orglett.6b03264.s004