Highly Enantioselective 1,4-Addition of
Diorganozinc Reagents to Cyclic
Enones Using Chiral Diphosphite
Ligands Derived from H<sub>8</sub>-Binaphthol
Liang
Terry T.-L. Au-Yeung
Albert S. C. Chan
10.1021/ol026581+.s002
https://acs.figshare.com/articles/journal_contribution/Highly_Enantioselective_1_4-Addition_of_Diorganozinc_Reagents_to_Cyclic_Enones_Using_Chiral_Diphosphite_Ligands_Derived_from_H_sub_8_sub_-Binaphthol/4008033
High enantioselectivities have been achieved in the 1,4-addition of dialkylzincs to 2-cyclopentenone, 2-cyclohexenone, and 2-cycloheptenone
with ee values up to 99% by using chiral aryl diphosphite ligands derived from H<sub>8</sub>-binaphthol.
2002-10-10 00:00:00
Chiral Diphosphite Ligands Derived
chiral aryl diphosphite ligands
H 8
2-
Binaphthol High enantioselectivities