Iron-Mediated Annulation
between Methylene Ketones and Diethanolamines: A Sustainable and Scalable
Procedure toward <i>N</i>‑(2-Hydroxyethyl) Pyrroles
Weiming Hu
Jin-Tao Yu
Dengman Ye
Zhou Zhou
Song Sun
Jiang Cheng
10.1021/acs.joc.6b01195.s002
https://acs.figshare.com/articles/journal_contribution/Iron-Mediated_Annulation_between_Methylene_Ketones_and_Diethanolamines_A_Sustainable_and_Scalable_Procedure_toward_i_N_i_2-Hydroxyethyl_Pyrroles/3830832
An
iron-mediated direct annulation between methylene ketones and diethanolamines
was developed for the efficient synthesis of <i>N</i>-(2-hydroxyethyl)
pyrroles. This protocol shows high efficiency, operational simplicity,
good functional group compatibility as well as broad substrates scope.
2016-09-07 00:00:00
Iron-Mediated Annulation
pyrrole
methylene ketones
group compatibility
annulation
substrates scope
Hydroxyethyl
synthesis
simplicity
Diethanolamine
Scalable Procedure
efficiency
iron-mediated
Sustainable
hydroxyethyl
diethanolamine
Pyrrole
Methylene Ketones