Diastereoselective Preparation of Chiral-at-Metal
Organometallic Complexes Using a Chelating
Sulfoxide−Carboxylate Ligand
Michael Otto
Jonathan Parr
Alexandra M. Z. Slawin
10.1021/om9805887.s001
https://acs.figshare.com/articles/journal_contribution/Diastereoselective_Preparation_of_Chiral-at-Metal_Organometallic_Complexes_Using_a_Chelating_Sulfoxide_Carboxylate_Ligand/3783147
Using the bidentate ligand (<i>R</i>)-2-[(<i>R</i>)-phenylsulfinyl]propionic acid (<b>1</b>), a range of new chiral-at-metal complexes of general formula [(L)M(S,O)Cl] have
been prepared where L = Cp*, M = Rh<sup>III</sup> (<b>2</b>), Ir<sup>III</sup> (<b>3</b>), L
= <i>p</i>-cymene, M = Ru<sup>II</sup> (<b>4</b>), Os<sup>II</sup> (<b>5</b>), and L = C<sub>6</sub>(CH<sub>3</sub>)<sub>6</sub>,
M = Ru<sup>II</sup> (<b>6</b>) and S,O is the monoanion obtained from
the K(<i>t</i>-BuO) deprotonation of <b>1</b>. Molecular structures
for <b>2</b>−<b>6</b> are reported, confirming that these complexes
are formed with excellent stereospecificity at the metal
center in moderate (59%, <b>6</b>) to excellent (92%, <b>3</b>) isolated
single-isomer yields.
1998-09-24 00:00:00
complex
III
CH
Ru II