Homanen, Pertti Persson, Roger Haukka, Matti Pakkanen, Tapani A. Nordlander, Ebbe Cluster-Based Catalytic Hydrogenation with High Conversion and Reversible Enantioselectivity<sup>†</sup> Four tetranuclear ruthenium carbonyl hydrido clusters consisting of the enantiomeric pairs [H<sub>4</sub>Ru<sub>4</sub>(CO)<sub>10</sub>{μ-1,2-(<i>R</i>/<i>S</i>,<i>R</i>/<i>S</i>)-bdpp}] and [H<sub>4</sub>Ru<sub>4</sub>(CO)<sub>10</sub>{1,1-(<i>R</i>/<i>S</i>,<i>R</i>/<i>S</i>)-bdpp}] containing chiral (<i>R,R</i>)- or (<i>S,S</i>)-bdpp [bdpp = (2<i>R</i>/<i>S</i>,4<i>R</i>/<i>S</i>)-2,4-bis(diphenylphosphino)pentane] have been prepared and fully characterized. These clusters catalyze asymmetric hydrogenation of tiglic acid [<i>trans</i>-2-methyl-2-butenoic acid] with high conversion rates (75−100%) under relatively mild reaction conditions. Enantiomeric excesses of 40−46% were observed; the predominating enantiomeric form of the hydrogenated product is dependent on the configuration of the diphosphine ligand, indicating strong chiral induction. reaction conditions;enantiomeric pairs;High Conversion;Enantiomeric excesses;diphosphine ligand;hydrogenated product;tiglic acid;CO;H 4 Ru 4;tetranuclear ruthenium carbonyl hydrido clusters;bdpp;clusters catalyze;chiral induction;enantiomeric form 2000-12-01
    https://acs.figshare.com/articles/dataset/Cluster-Based_Catalytic_Hydrogenation_with_High_Conversion_and_Reversible_Enantioselectivity_sup_sup_/3762879
10.1021/om000367c.s001