Enzymatic Selective Dehydration and Skeleton Rearrangement of Paclitaxel Precursors Donghyun Lee Mahn-Joo Kim 10.1021/ol990179m.s001 https://acs.figshare.com/articles/journal_contribution/Enzymatic_Selective_Dehydration_and_Skeleton_Rearrangement_of_Paclitaxel_Precursors/3759744 Enzymatic dehydration reactions to remove selectively the chemically least reactive 13-hydroxyl group of 10-deacetylbaccatin III and its derivatives <b>2a</b><b>−</b><b>c</b> are described. The elimination of the 13-OH takes place with skeleton rearrangement, allowing us to synthesize some interesting diterpenoids in good yields. 1999-08-12 00:00:00 elimination Paclitaxel Precursors Skeleton Rearrangement derivatives 2 reactive III diterpenoid Enzymatic hydroxyl deacetylbaccatin OH yield dehydration reactions Dehydration skeleton rearrangement