%0 Journal Article %A Brummond, Kay M. %A Gao, Dong %D 2003 %T Unique Strategy for the Assembly of the Carbon Skeleton of Guanacastepene A Using an Allenic Pauson−Khand-Type Reaction %U https://acs.figshare.com/articles/journal_contribution/Unique_Strategy_for_the_Assembly_of_the_Carbon_Skeleton_of_Guanacastepene_A_Using_an_Allenic_Pauson_Khand-Type_Reaction/3748152 %R 10.1021/ol035322x.s002 %2 https://acs.figshare.com/ndownloader/files/5841513 %K tricyclic framework %K allenic %K Carbon Skeleton %K functionalized tricyclic core %K novel strategy %K Assembly %K Guanacastepene %K approach %K rhodium %K synthesis %K Pauson %K guanacastepene %K Unique Strategy %K formation %K intially %K Allenic %X An approach to the highly functionalized tricyclic core of guanacastepene A has been developed using a rhodium(I)-catalyzed allenic Pauson−Khand reaction. This approach constitutes a conceptually novel strategy for the synthesis of this tricyclic framework, whereby the six-membered ring is formed intially followed by simultaneous formation of the five- and seven-membered rings. %I ACS Publications