%0 Journal Article %A Bates, Craig G. %A Gujadhur, Rattan K. %A Venkataraman, D. %D 2002 %T A General Method for the Formation of Aryl−Sulfur Bonds Using Copper(I) Catalysts %U https://acs.figshare.com/articles/journal_contribution/A_General_Method_for_the_Formation_of_Aryl_Sulfur_Bonds_Using_Copper_I_Catalysts/3743616 %R 10.1021/ol0264105.s001 %2 https://acs.figshare.com/ndownloader/files/5836980 %K General Method %K NaO t %K aryl iodides %K aryl sulfides %K Bu %K Formation %K Catalyst %K thiol %K CuI %K neocuproine %K Aryl %K mol %K toluene %K Bond %K variety %K yield %X We report a mild, palladium-free synthetic protocol for the cross-coupling reaction of aryl iodides and thiols using 10 mol % CuI and 10 mol % neocuproine, with NaOt-Bu as the base, in toluene at 110 °C. Using this protocol, we have shown that a variety of aryl sulfides can be synthesized in excellent yields from readily available iodides and thiols. %I ACS Publications