%0 Journal Article %A Fridman, Micha %A Solomon, Dmitry %A Yogev, Shay %A Baasov, Timor %D 2001 %T One-Pot Synthesis of Glucosamine Oligosaccharides %U https://acs.figshare.com/articles/journal_contribution/One-Pot_Synthesis_of_Glucosamine_Oligosaccharides/3741252 %R 10.1021/ol017054d.s002 %2 https://acs.figshare.com/ndownloader/files/5833020 %K glycosyl donors %K manner %K ethylthio %K anomeric %K NPhth %K glycosylation %K introduction %K reactivity %K sequential %K tetrasaccharide %K glucose %K yield %K phenylthio %K trisaccharide %K NHTroc %K oligosaccharide synthesis %K Glucosamine Oligosaccharides Tuning %K Synthesi %X Tuning the reactivity of glycosyl donors derived from 2-amino-2-deoxy glucose by selective introduction of different N-protecting (NPhth and NHTroc) and anomeric leaving groups (ethylthio and phenylthio) enabled highly efficient oligosaccharide synthesis in a one-pot manner. One-pot sequential glycosylation of three and four units of 2-amino-2-deoxy glucose gave trisaccharides and tetrasaccharide in 50−81% yields. %I ACS Publications