10.1021/ol015814e.s001 Michael A. Calter Michael A. Calter Xin Guo Xin Guo Wensheng Liao Wensheng Liao One-Pot, Catalytic, Asymmetric Synthesis of Polypropionates American Chemical Society 2001 aldol reactions Asymmetric Synthesis syn dipropionate aldol adducts aldol adducts methylketene dimer 2001-04-10 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/One-Pot_Catalytic_Asymmetric_Synthesis_of_Polypropionates/3739023 The opening of methylketene dimer, followed by aldol reactions of the resulting enolate, provides a convenient access to <i>syn</i>,<i>syn</i>-dipropionate aldol adducts of a variety of aldehydes. These aldol adducts are useful precursors in the synthesis of complex polypropionates.