10.1021/ol015814e.s001
Michael A. Calter
Michael A.
Calter
Xin Guo
Xin
Guo
Wensheng Liao
Wensheng
Liao
One-Pot, Catalytic, Asymmetric
Synthesis of Polypropionates
American Chemical Society
2001
aldol reactions
Asymmetric Synthesis
syn
dipropionate aldol adducts
aldol adducts
methylketene dimer
2001-04-10 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/One-Pot_Catalytic_Asymmetric_Synthesis_of_Polypropionates/3739023
The opening of methylketene dimer, followed by aldol reactions of the resulting enolate, provides a convenient access to <i>syn</i>,<i>syn</i>-dipropionate
aldol adducts of a variety of aldehydes. These aldol adducts are useful precursors in the synthesis of complex polypropionates.