10.1021/ol015813m.s001
Klemens Högenauer
Klemens
Högenauer
Johann Mulzer
Johann
Mulzer
A Novel Palladium-Catalyzed
Intramolecular Redox Reaction
American Chemical Society
2001
intramolecular arylpalladium enolate
series
acyclic substrates
Redox
silyl enol ethers
mechanism
palladium acetate
redox
scope
type
HBr
oxidation
bromobenzyl
formation
enone
limitation
Intramolecular
2001-04-05 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/A_Novel_Palladium-Catalyzed_Intramolecular_Redox_Reaction/3739020
A new type of palladium-catalyzed redox reaction is described, forming enones from 2-(2-bromobenzyl)-ketones with an overall loss of HBr.
The scope and limitations of the reaction are demonstrated by a series of cyclic and acyclic substrates. The mechanism most probably
involves the formation of an intramolecular arylpalladium enolate and is related to the oxidation of silyl enol ethers with palladium acetate.