Liu, Shi-Xia Michel, Christoph Schmittel, Michael A Highly Regioselective Sonogashira Coupling as a Key Step in the Preparation of the First Phenanthroline with Two Diverse Reactive Groups in 3,8-Positions The preparation of 3,8-unsymmetric phenanthrolines is described. Desymmetrization of 3,8-dibromophenanthroline was achieved after monoarylation followed by regioselective Pd-catalyzed monoalkynylation that was controlled by the methoxy group of the dimethoxyphenyl substituent. phenanthroline;Desymmetrization;Diverse Reactive Groups;Key Step;regioselective;methoxy group;First Phenanthroline;Regioselective Sonogashira;Preparation;dibromophenanthroline;dimethoxyphenyl substituent;preparation;monoarylation;unsymmetric;monoalkynylation 2000-11-11
    https://acs.figshare.com/articles/journal_contribution/A_Highly_Regioselective_Sonogashira_Coupling_as_a_Key_Step_in_the_Preparation_of_the_First_Phenanthroline_with_Two_Diverse_Reactive_Groups_in_3_8-Positions/3737256
10.1021/ol006514k.s001