Frederico, Daniel Marcos Donate, Paulo Constantino, Mauricio Gomes Bronze, Erika Soares I. Sairre, Mirela A Short and Efficient Synthesis of Crocetin-dimethylester and Crocetindial In this paper we describe an efficient six-step synthesis of crocetin-dimethylester that could be further reduced to a “four-step” synthesis through the use of in situ procedures. The simplicity of the whole process, the ready availability of starting materials, and the high overall yield render this strategy a very attractive synthesis of this very important compound, which is the key intermediate for the synthesis of several carotenoids and other polyene natural products. compound;availability;strategy;Efficient Synthesis;synthesis;simplicity;Short;material;carotenoid;polyene;Crocetindial;procedure 2003-10-23
    https://acs.figshare.com/articles/journal_contribution/A_Short_and_Efficient_Synthesis_of_Crocetin-dimethylester_and_Crocetindial/3699771
10.1021/jo034545y.s002