%0 Journal Article
%A Rao, U. Narasimha
%A Biehl, Ed
%D 2002
%T Facile Preparation of Benzo[4,5]thieno[2,3-b]pyridines and
Naphtho[b-4,5]thieno[2,3-b]pyridines via the Reaction of Barton
Esters and Benzynes
%U https://acs.figshare.com/articles/journal_contribution/Facile_Preparation_of_Benzo_4_5_thieno_2_3-_i_b_i_pyridines_and_Naphtho_i_b_i_-4_5_thieno_2_3-_i_b_i_pyridines_via_the_Reaction_of_Barton_Esters_and_Benzynes/3692994
%R 10.1021/jo016407j.s001
%2 https://acs.figshare.com/ndownloader/files/5783355
%K pyridine
%K compound
%K Barton esters
%X Titled compounds were prepared in a one-pot synthesis by generating symmetrically substituted
benzyne intermediates by the diazotization of anthranilic acids in the presence of Barton esters.
Unsymmetrically substituted aryne either gave mixtures of regioisomers or failed. However, nitro
and methyl derivatives of titled compounds could be obtained as single products using appropriately
substituted Barton esters.
%I ACS Publications