%0 Journal Article %A Yuan, Chenguang %A Williams, Robert M. %D 1997 %T Total Synthesis of the Anti Methicillin-Resistant Staphylococcus aureus Peptide Antibiotics TAN-1057A-D %U https://acs.figshare.com/articles/journal_contribution/Total_Synthesis_of_the_Anti_Methicillin-Resistant_i_Staphylococcus_aureus_i_Peptide_Antibiotics_TAN-1057A-D/3667221 %R 10.1021/ja972670j.s001 %2 https://acs.figshare.com/ndownloader/files/5756952 %K convergent route %K Staphylococcu %K PK %K TAN %K bacteria Flexibacter sp %K aureus %K cyclic amidinourea %K Total Synthesis %X TAN-1057A−D, dipeptides isolated from bacteria Flexibacter sp. PK-74 and PK-176, are new antibiotics with potent antibacterial activity against methicillin-resistant Staphylococcus aureus. We describe, in detail, the total synthesis of TAN-1057A−D by a convergent route featuring a new method to construct the cyclic amidinourea functional group. %I ACS Publications