%0 Journal Article
%A Yuan, Chenguang
%A Williams, Robert M.
%D 1997
%T Total Synthesis of the Anti Methicillin-Resistant Staphylococcus
aureus Peptide Antibiotics TAN-1057A-D
%U https://acs.figshare.com/articles/journal_contribution/Total_Synthesis_of_the_Anti_Methicillin-Resistant_i_Staphylococcus_aureus_i_Peptide_Antibiotics_TAN-1057A-D/3667221
%R 10.1021/ja972670j.s001
%2 https://acs.figshare.com/ndownloader/files/5756952
%K convergent route
%K Staphylococcu
%K PK
%K TAN
%K bacteria Flexibacter sp
%K aureus
%K cyclic amidinourea
%K Total Synthesis
%X TAN-1057A−D, dipeptides isolated from bacteria
Flexibacter sp. PK-74 and PK-176, are new
antibiotics
with potent antibacterial activity against methicillin-resistant
Staphylococcus aureus. We describe, in detail,
the
total synthesis of TAN-1057A−D by a convergent route featuring a new
method to construct the cyclic amidinourea
functional group.
%I ACS Publications