Liao, Lian-an Fox, Joseph M. A Copper-Catalyzed Method for the Facially Selective Addition of Grignard Reagents to Cyclopropenes A Cu-catalyzed method for the addition of Grignard reagents to 1-alkyl-3-hydroxymethylcyclopropenes and their MOM ethers is described. The face of addition is syn relative to the hydroxymethyl and alkoxymethyl groups. Excellent diastereoselectivity is observed for a range of alkyl, alkenyl, and alkynylmagnesium halides. The addition reactions create chiral all-carbon quaternary centers, and the cyclopropylmetals that are generated can be reacted with electrophiles to produce highly functionalized cyclopropanes. Grignard reagents;MOM ethers;Grignard Reagents;Excellent diastereoselectivity;alkynylmagnesium halides;addition reactions;functionalized cyclopropanes;alkyl;alkoxymethyl groups 2002-11-06
    https://acs.figshare.com/articles/journal_contribution/A_Copper-Catalyzed_Method_for_the_Facially_Selective_Addition_of_Grignard_Reagents_to_Cyclopropenes/3645618
10.1021/ja0278234.s002