%0 Journal Article
%A Niu, Guangle
%A Liu, Weimin
%A Zhou, Bingjiang
%A Xiao, Hongyan
%A Zhang, Hongyan
%A Wu, Jiasheng
%A Ge, Jiechao
%A Wang, Pengfei
%D 2016
%T Deep-Red and Near-Infrared
Xanthene Dyes for Rapid
Live Cell Imaging
%U https://acs.figshare.com/articles/journal_contribution/Deep-Red_and_Near-Infrared_Xanthene_Dyes_for_Rapid_Live_Cell_Imaging/3571236
%R 10.1021/acs.joc.6b00981.s003
%2 https://acs.figshare.com/ndownloader/files/5649075
%K cell imaging
%K Live cell imaging data
%K xanthene dyes
%K imaging properties
%K HeLa cells
%K theory calculations
%K Rapid Live Cell Imaging
%K fluorescence quantum yields
%X In
this work, two xanthene dyes (H-hNR and TF-hNR) have been synthesized by a convenient and efficient method. These
two dyes exhibited deep-red and near-infrared emissions, high fluorescence
quantum yields, and good photostability. Their structure–optical
properties were investigated by X-ray crystal structure analysis and
density functional theory calculations. Live cell imaging data revealed
that H-hNR and TF-hNR could rapidly stain
both A549 and HeLa cells with low concentrations. The excellent photophysical
and imaging properties render them as promising candidates for use
in live cell imaging.
%I ACS Publications