Chen, Xiaohong Liu, Xiaoguang Mohr, Justin T. Cu-Catalyzed Stereoselective γ‑Alkylation of Enones A general regio- and stereoselective γ-C–C bond formation is achieved using α-halocarbonyl compounds and dienol ethers via Cu­(II) catalysis. This method constitutes a novel approach to the challenging 1,6-dioxygenation motif. A range of γ-substituted enones, including many bearing all-carbon quaternary centers, are available through a simple protocol under mild reaction conditions with superb functional group compatibility. Excellent stereoinduction is observed providing controlled access to challenging stereochemical arrays. reaction conditions;motif;stereoselective;dienol ethers;halocarbonyl;novel approach;Excellent stereoinduction;Alkylation;dioxygenation;group compatibility;access;method;Enone;quaternary;catalysi;regio;formation;compound;enone;center;Stereoselective;stereochemical arrays;Cu;bond 2016-05-09
    https://acs.figshare.com/articles/journal_contribution/Cu_Catalyzed_Stereoselective_Alkylation_of_Enones/3382297
10.1021/jacs.6b02565.s001