Cu-Catalyzed Stereoselective γ‑Alkylation of Enones Xiaohong Chen Xiaoguang Liu Justin T. Mohr 10.1021/jacs.6b02565.s001 https://acs.figshare.com/articles/journal_contribution/Cu_Catalyzed_Stereoselective_Alkylation_of_Enones/3382297 A general regio- and stereoselective γ-C–C bond formation is achieved using α-halocarbonyl compounds and dienol ethers via Cu­(II) catalysis. This method constitutes a novel approach to the challenging 1,6-dioxygenation motif. A range of γ-substituted enones, including many bearing all-carbon quaternary centers, are available through a simple protocol under mild reaction conditions with superb functional group compatibility. Excellent stereoinduction is observed providing controlled access to challenging stereochemical arrays. 2016-05-09 00:00:00 reaction conditions motif stereoselective dienol ethers halocarbonyl novel approach Excellent stereoinduction Alkylation dioxygenation group compatibility access method Enone quaternary catalysi regio formation compound enone center Stereoselective stereochemical arrays Cu bond