Intramolecular Iron-Mediated Diene/Olefin Cyclocoupling: Formation of
Carbon Spirocycles
Anthony J. Pearson
Xiaolong Wang
Ismet B. Dorange
10.1021/ol040036m.s001
https://acs.figshare.com/articles/journal_contribution/Intramolecular_Iron_Mediated_Diene_Olefin_Cyclocoupling_Formation_of_Carbon_Spirocycles/3331375
A short and convenient diastereoselective synthesis of all-carbon spirocylic molecules was developed. A straightforward protocol that involves
rearrangement of the diene−Fe(CO)<sub>3</sub> complex followed by cyclization delivers the desired product. The reaction substrates were easily prepared
by reaction of an appropriate nucleophile and a cyclohexadienyl-Fe(CO)<sub>3</sub> cation.
2004-07-22 00:00:00
spirocylic
diene
reaction substrates
cyclization
Formation
molecule
Cyclocoupling
diastereoselective synthesis
nucleophile
Carbon Spirocycles
Diene
cation
Intramolecular
rearrangement