Brunner, Jens Kraemer, Roland Copper(II)-Quenched Oligonucleotide Probes for Fluorescent DNA Sensing A copper(II)-quenched molecular beacon was prepared by attaching fluorescein to the 3‘-end and a copper(II) complex to the 5‘-end of DNA. In the presence of complementary DNA, copper(II) and dye are spatially separated in the duplex and fluorescence increases up to 15-fold, with excellent discrimination of single base mismatches. base mismatches;Fluorescent DNA;fluorescence increases 2004-10-27
    https://acs.figshare.com/articles/journal_contribution/Copper_II_Quenched_Oligonucleotide_Probes_for_Fluorescent_DNA_Sensing/3319213
10.1021/ja047252a.s001