10.1021/jo0500939.s001 Ana Minatti Ana Minatti Karl Heinz Dötz Karl Heinz Dötz Enantioselective Total Synthesis of (−)-Curcuquinone via Regioselective Chromium-Mediated Benzannulation American Chemical Society 2005 Enantioselective Regioselective Curcuquinone curcuhydroquinone monomethyl ether 9 Benzannulation enantioselective regioselective curcuquinone strategy synthesis protection benzannulation reaction marine isolation Synthesi 2005-04-29 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Enantioselective_Total_Synthesis_of_Curcuquinone_via_Regioselective_Chromium_Mediated_Benzannulation/3288775 A short and efficient, high-yielding enantioselective total synthesis of the marine natural product (−)-curcuquinone <b>1</b> is reported involving a regioselective [3 + 2 + 1]-benzannulation reaction as the key step. Additionally, this strategy allows the isolation of curcuhydroquinone monomethyl ether <b>9</b> as an intermediate of the benzannulation reaction and its subsequent further protection toward diversified hydroquinones.